Drug Name

Orlistat (Pills for weight loss)

Drug Uses
Pills for weight loss Orlistat is a drug, used in combination with diet for weight control at patients with hypertension, diabetes and high level of cholesterol..

How to use
Administer pills of Orlistat under your physicians recommendations. Read the instruction for your Pills for weight loss (Orlistat). If your weight is equal to your height or more than it - you can start to use the drug. Take Orlistat internally every time when you eat fatty foods. Dont administer Orlistat if you dont eat meals without fat or containing low amount of it. Pills for weight loss Orlistat can diminish levels of vitamins, so it is necessary to take multivitamins once a day.

Drug Class and Mechanism
The unique molecular structure of pills for weight loss Orlistat allows it to bind and inhibit lipase, which is involve in the digestion of fats. Orlistat blocks digestion of about 25% of fat, containing in the eaten food.

Missed Dose
Take your missed dose of Orlistat drug as soon as possible, dont take more than your regular dose.

Storage
You should store your pills for weight loss Orlistat at 68 - 77F (20 - 25С), away from pets and children, in protected from moisture and high temperature place.

Warnings/Precautions
Dont administer Orlistat in such cases: You have allergic reactions to Orlistat ingridients; Your weight is in normal condition; You have problems with food digestion; You have had transplantation of organs; You use cyclosporine. Important: Dont exceed recommended dose to avoid undesirable side effects. Choosing the right diet and exercise are an important factor in the course of treatment with Orlistat drug, so follow all your physicians prescriptions. Orlistat can lead to changes in functioning of your bowel (oily spotting, oily or fatty stool, increased meteorism). In such case eat more low-fat food. Pills for weight loss Orlistat may have an impact on blood sugar levels at patients with diabetes, so it is necessary to check sugar level. Orlistat drug therapy is not recommended at patients younger 18. Intake of Orlistat is contraindicative if you are pregnant or breast-feeding.

Possible Side Effects
Several slight side effects can be observed: Meteorism; frequent defecation; diarrhea. Stop taking Orlistat drug if there is serious allergic reactions. Symptoms of a serious allergic reaction: rash, itching, swelling of the face, tongue and throat), strong dizziness, troubles with breathing.

More Information
Pharmacodynamics The drug is highly lipophilic and is mixed with drops of fat. Orlistat covalently binds to the active center of pancreatic and gastric lipases, thereby inactivating them. In view of the inhibition of gastrointestinal lipases kishnyh triglycerides can not penetrate into the blood. This causes an energy deficit that leads to mobilization of fat from the fat deposits. Under the influence of Orlistat viscero-abdominal fat is mainly reduced. Orlistat also reduces cholesterol levels - due to lower amount of free fatty acids and monoglycerides in the intestinal lumen - the solubility of cholesterol decreases, which reduces its ability to penetrate into the blood. Due to the normalization of the lipid composition of the blood insulin sensitivity increases, hyperinsulinemia decreases, which also helps to reduce the mass of viscero-abdominal fat. According to the multi-center placebo controlled study, after 52 weeks of standard doses of pills for weight loss Orlistat, weight decreased by 6.2% from the initial, level of insulin was reduced by 18%. If you are taking any of the following drugs, inform your doctor before starting to use Orlistat: Drugs, containing dimenhydrinate ((Dramamine), atropine (Donnatal), scopolamine (Transderm-Scop), methscopolamine (Pamine) benztropine (Cogentin)); Bronchodilators, containing tiotropium (Spiriva), ipratroprium (Atrovent); Mepenzolate (Cantil); Glycopyrrolate (Robinul); Drugs for therapy of bladder and urinary tract (Solifenacin (Vesicare), flavoxate (Urispas), tolterodine (Detrol), oxybutynin (Ditropan, Oxytrol), darifenacin (Enablex); Drugs, irritating bowel (hyoscyamine (Anaspaz, Cystospaz, Levsin), propantheline (Pro-Banthine), dicyclomine (Bentyl)). This list is not complete and there may be other drugs that can interact with pills for weight loss “Orlistat”. Tell your physician about all the medicines, minerals, herbal products, vitamins and medicines, that were prescibed by other doctors.